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1 Frequently Asked Questions with the term “child”

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Where can I get a vaccination appointment for COMIRNATY?

You can get a vaccine at a healthcare provider’s office, pharmacies, some hospitals, and health clinics throughout the United States.

Talk to your doctor and click here to find and schedule a COVID-19 shot, if eligible.

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Why is it important to stay up to date with COVID-19 vaccination in accordance with CDC recommendations?
The protection you get against COVID-19 from previous vaccination or infection decreases as time goes on and as the virus that causes COVID-19 evolves. This can leave you at increased risk for COVID-19. That’s why getting the 2025-2026 COVID-19 shot is one of the best ways for you and your child to help protect yourselves. To learn more about how our vaccine is given, see our Dosing Guide.

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Have the COVID-19 vaccines from BioNTech and Pfizer been studied?

Yes. The COVID-19 vaccines from BioNTech and Pfizer have been rigorously tested in clinical trials.

Learn more about the clinical trials here.

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What should you tell the vaccination provider before you or your child get COMIRNATY?

Tell your vaccination provider about all of your medical conditions, including if you:

  • Have any allergies
  • Had a severe allergic reaction after receiving a previous dose of any COVID-19 vaccine
  • Have had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart)
  • Have a fever
  • Have a bleeding disorder or are on a blood thinner
  • Are immunocompromised or are on a medicine that affects your immune system
  • Are pregnant, plan to become pregnant, or are breastfeeding
  • Have received another COVID‑19 vaccine
  • Have ever fainted in association with an injection

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How do mRNA vaccines like COMIRNATY work?

COVID-19 vaccines help the body develop an immune response to the virus that causes COVID-19 without having to get the infection. mRNA vaccines provide instructions to the body to make a protein found on the surface of the virus. This triggers an immune response inside the body and trains the immune system to recognize and help fight the virus in the future.

Learn more about how COMIRNATY works.

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Why was the formula of COMIRNATY updated?

The formula of COMIRNATY was updated as recommended by the FDA to closely match recently circulating strains of the virus that causes COVID-19.

Due to the nature of mRNA design and production, COMIRNATY can be updated in a timely manner.

Updated formulas of COMIRNATY are made using the same process as previous formulas, with the difference only in the mRNA, which encodes the viral spike protein.

Learn more about how COMIRNATY works.

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Can COMIRNATY make you sick with COVID-19?
COMIRNATY does not contain SARS-CoV-2, the virus that causes COVID-19. COMIRNATY cannot give you COVID-19.

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Can the mRNA vaccine technology change my DNA?
The vaccines do not change or interact with your DNA in any way.

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Were there clinical trials done for COMIRNATY?

Yes, multiple clinical trials contributed to testing COMIRNATY.

Learn more about the clinical trials here.

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What is known about the safety of COMIRNATY?

COMIRNATY has been tested in multiple clinical trials with a demonstrated safety profile. Serious risks can include severe allergic reactions, myocarditis (inflammation of the heart muscle), or pericarditis (inflammation of the lining outside the heart). Some people may faint after vaccination, and people with weakened immune systems may have a reduced immune response.

Common side effects in people 5 years of age and older include pain, swelling or redness where the shot is given, tiredness (fatigue), headaches, chills, muscle and/or joint pain, and fever.

Other side effects reported: nausea, feeling unwell, swollen lymph nodes (lymphadenopathy), decreased appetite, diarrhea, vomiting, dizziness, and febrile seizures (convulsions during a fever) in children 5 through 11 years of age. Learn more about safety.

These may not be all the possible side effects of COMIRNATY. Ask your healthcare provider about any side effects that concern you.

The CDC, FDA, and other federal agencies continue to rigorously monitor the safety of COVID‑19 vaccines, including COMIRNATY, and share information with the public as it becomes available. Learn more from the CDC.

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Who should get COMIRNATY?

COMIRNATY is approved for use in individuals who are 65 years of age and older, or 5 years through 64 years of age with at least one underlying condition that puts them at high risk for severe outcomes from COVID-19.

Talk to your doctor and click here to find and schedule a COVID-19 shot, if eligible.

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Who should NOT get COMIRNATY?
You should NOT get COMIRNATY if you had a severe allergic reaction after a previous dose of any COMIRNATY or Pfizer-BioNTech COVID-19 vaccines or to any ingredients in these vaccines.

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What are the benefits of COMIRNATY?
The FDA approved COMIRNATY as a vaccine for use in people 5 years of age and older to help protect against COVID-19.

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