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Understanding COMIRNATY safety information

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COMIRNATY® is a vaccine to protect against coronavirus disease 2019 (COVID-19). COMIRNATY is for people who are:

  • 65 years of age and older, or
  • 5 years through 64 years of age at high risk for severe COVID-19.



Learn more about underlying conditions and risk factors that put individuals at high risk for severe outcomes from COVID‑19 here.

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Side Effects & Safety

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Serious risks of COMIRNATY can include:

  • Severe allergic reactions
  • Myocarditis (inflammation of the heart muscle)
  • Pericarditis (inflammation of the lining outside the heart)
  • Some people may faint after vaccination, and people with weakened immune systems may have a reduced immune response.

Common side effects of COMIRNATY can include:

  • Pain, swelling, or redness where the shot is given
  • Tiredness (fatigue)
  • Headache
  • Chills
  • Muscle and/or joint pain
  • Fever

Other side effects reported:

  • Nausea
  • Feeling unwell
  • Swollen lymph nodes (lymphadenopathy)
  • Decreased appetite
  • Diarrhea
  • Vomiting
  • Dizziness
  • Febrile seizures (convulsions during a fever) in children 5 through 11 years of age
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The CDC, FDA, and other federal agencies rigorously monitor the safety of COVID-19 vaccines and share information with the public as soon as it becomes available.
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Learn more from the CDC
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These may not be all the possible side effects of COMIRNATY. Ask your healthcare provider about any side effects that concern you.
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What Should You Tell the Vaccination Provider Before You or Your Child Gets COMIRNATY?

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Tell your vaccination provider about all of your medical conditions, including if you or your child:

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  • Have any allergies
  • Had a severe allergic reaction after receiving a previous dose of any COVID-19 vaccine
  • Have had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart)
  • Have a fever
  • Have a bleeding disorder or are on a blood thinner
  • Are immunocompromised or are on a medicine that affects your immune system
  • Are pregnant, plan to become pregnant, or are breastfeeding
  • Have received another COVID‑19 vaccine
  • Have ever fainted in association with an injection
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Stay Informed About COVID‑19 and COMIRNATY

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