Understanding COMIRNATY
safety information for
someone you care for
COMIRNATY® (COVID-19 Vaccine, mRNA) is a vaccine to protect against coronavirus disease 2019 (COVID-19). COMIRNATY is for people who are:
• 65 years of age and older, or
• 5 years through 64 years of age at high risk for severe COVID-19.
See the latest CDC recommendations for COVID-19 vaccination here.
Side Effects & Safety
The CDC, FDA, and other federal agencies rigorously monitor the safety of COVID-19 vaccines and share information with the public as soon as it becomes available.
Serious risks of COMIRNATY can include:
- Severe allergic reactions
- Myocarditis (inflammation of the heart muscle)
- Pericarditis (inflammation of the lining outside the heart)
Some people may faint after vaccination, and people with weakened immune systems may have a reduced immune response.
Common side effects of COMIRNATY in people 5 years of age and older include:
- Pain, swelling, or redness where the shot is given
- Tiredness (fatigue)
- Headache
- Chills
- Muscle and/or joint pain
- Fever
Other side effects reported:
- Nausea
- Feeling unwell
- Swollen lymph nodes (lymphadenopathy)
- Decreased appetite
- Diarrhea
- Vomiting
- Dizziness
- Febrile seizures (convulsions during a fever) in children 5 through 11 years of age
These may not be all the possible side effects of COMIRNATY. Ask your healthcare provider about any side effects that concern you.
The CDC, FDA, and other federal agencies rigorously monitor the safety of COVID-19 vaccines and share information with the public as soon as it becomes available.
What Should You Tell the Vaccination Provider Before You or Your Child Gets COMIRNATY?
Tell your vaccination provider about all of your medical conditions, including if you or your child (5 years of age and older):
- Have any allergies
- Had a severe allergic reaction after receiving a previous dose of any COVID-19 vaccine
- Have had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart)
- Have a fever
- Have a bleeding disorder or are on a blood thinner
- Are immunocompromised or are on a medicine that affects your immune system
- Are pregnant, plan to become pregnant, or are breastfeeding
- Have received another COVID‑19 vaccine
- Have ever fainted in association with an injection
COMIRNATY has been tested in multiple clinical trials with a demonstrated safety profile.
Learn more about the COMIRNATY clinical trials
From You